Big and high dimensional data with complex structures are emerging steadily and rapidly over the last few years. A relative new data analysis method that aims to discover meaningful patterns in a big data matrix is {\it biclustering}. This method applies clustering simultaneously on 2 dimensions of a data matrix and aims to find a subset of rows for which the response profile is similar across a subset of columns in the data matrix. This results in a submatrix called a bicluster. The package \texttt{RcmdrPlugin.BiclustGUI} is a GUI plug-in for R Commander for biclustering. It combines different biclustering packages to provide many algorithms for data analysis, visualisations and diagnostics tools in one unified framework. By choosing R Commander, the BiclustGUI produces the original R code in the background while using the interface; this is useful for more experienced R users who would like to transition from the interface to actual R code after using the algorithms. Further, the BiclustGUI package contains template scripts that allow future developers to create their own biclustering windows and include them in the package. The BiclustGUI is available on CRAN and on R-Forge. The GUI also has a Shiny implementation including all the main functionalities. Lastly the template scripts have been generalized in the \texttt{REST} package, a new helping tool for creating R Commander plug-ins.
